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Science 1 March 1974:
Vol. 183. no. 4127, pp. 862 - 864
DOI: 10.1126/science.183.4127.862
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Articles

Brain Hyaluronidase: Changes in Activity during Chick Development

Jon R. Polansky 1, Bryan P. Toole 1, and Jerome Gross 1

1 Developmental Biology Laboratory, Departments of Medicine and Biological Chemistry, Harvard Medical School and Massachusetts General Hospital, Boston 02114

Development of embryonic chick brain is characterized by high levels of hyaluronidase activity and of hyaluronate, both of which decrease rapidly soon after the chick hatches. By analogy to other systems, it is proposed that the sequence of hyaluronate production and its enzymatic removal may have a developmental role in brain formation.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Separation and Properties of Rabbit Buccal Mucosal Wound Hyaluronidase.
C.N. Bertolami, R.H. Day, and D.G. Ellis (1986)
Journal of Dental Research 65, 939-944
   Abstract »    PDF »
Identification and Characterization of Rabbit Buccal Mucosal Hyaluronidase.
C.N. Bertolami and D.G. Ellis (1985)
Journal of Dental Research 64, 913-918
   Abstract »    PDF »
Mucopolysaccharidase Activity and Glycosaminoglycan Content in Traumatized Resorbing Deciduous Teeth.
S. A. Alexander and M. Swerdloff (1980)
Journal of Dental Research 59, 766-770
   Abstract »    PDF »


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