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Science 1 February 1974:
Vol. 183. no. 4123, pp. 435 - 437
DOI: 10.1126/science.183.4123.435
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Articles

Calcium Ion Release in Mechanically Disrupted Heart Cells

W. Glenn L. Kerrick 1 and Philip M. Best 1

1 Department of Physiology and Biophysics, School of Medicine, University of Washington, Seattle 98195

In cardiac muscle fibers which have had their sarcolemma disrupted intracellular stores of calcium ions can be released by the same chemical stimuli which cause their release from the sarcoplasmic reticulum of skinned skeletal muscle fibers. These stimuli are increases in calcium or caffeine concentrations and substitution of chloride for propionate or sodium for potassium in solutions bathing the fibers.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cardiac pacemaking: an obligatory role of catecholamines?.
G. Pollack (1977)
Science 196, 731-738
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Science. ISSN 0036-8075 (print), 1095-9203 (online)