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Science 25 January 1974:
Vol. 183. no. 4122, pp. 330 - 332
DOI: 10.1126/science.183.4122.330
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Articles

Spheroid Chromatin Units (ngr Bodies)

Ada L. Olins 1 and Donald E. Olins 1

1 University of Tennessee-Oak Ridge Graduate School of Biomedical Sciences, and Biology Division, Oak Ridge National Laboratory, Oak Ridge, Tennessee 37830

Linear arrays of spherical chromatin particles (ngr bodies) about 70 angstroms in diameter have been observed in preparations of isolated eukaryotic nuclei swollen in water, centrifuged onto carbon films, and positively or negatively stained. These bodies have been found in isolated rat thymus, rat liver, and chicken erythrocyte nuclei. Favorable views also reveal connecting strands about 15 angstroms wide between adjacent particles.


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Histone H1 Involvement in the Structure of the Chromosome Fiber.
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Cold Spring Harb Symp Quant Biol 42, 245-252
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H1 Histone and the Condensation of Chromatin and DNA.
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Nucleosomes, Histone Interactions, and the Role of Histones H3 and H4.
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Nucleosome Structure II: Structure of the SV40 Minichromosome and Electron Microscopic Evidence for Reversible Transitions of the Nucleosome Structure.
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Molecular Architecture of the Chromatin Fiber.
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{nu} Bodies Are Close-packed in Chromatin Fibers.
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Metaphase Chromosome Structure: The Role of Nonhistone Proteins.
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Histone Organization in Chromatin: Comparisons of Nucleosomes and Subnucleosomal Particles from Erythrocyte, Myeloma, and Yeast Chromatin.
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Histones and Chromatin Structure in Tetrahymena Macro- and Micronuclei.
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Morphology of Transcriptionally Active Chromatin.
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Summary: The Molecular Biology of the Eukaryotic Genome Is Coming of Age.
P. Chambon (1978)
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Hydrodynamic evidence in support of spacer regions in chromatin.
K. Schmitz and B. Shaw (1977)
Science 197, 661-663
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Reconstitution of chromatin subunits.
C. Woodcock (1977)
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Ribosomal genes of Xenopus laevis: evidence of nucleosomes in transcriptionally active chromatin.
R Reeves (1976)
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Chromosomal subunits in active genes have an altered conformation.
H Weintraub and M Groudine (1976)
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Cross-linking of DNA in situ as a probe for chromatin structure.
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Stage-specific switches in histone synthesis during embryogenesis of the sea urchin.
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Processing of newly synthesized histone molecules.
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Yeast chromatin subunit structure.
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Chromatin Structure: Deduced from a Minichromosome.
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Chromatin fragments resembling v bodies.
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Chromatin Structure: A Repeating Unit of Histones and DNA.
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