Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 18 January 1974:
Vol. 183. no. 4121, pp. 213 - 215
DOI: 10.1126/science.183.4121.213
Prev | Table of Contents | Next

Articles

Miniature End Plate Potentials Recorded from Mammalian Myoneural Junctions in vivo

Theodore B. Hoekman 1, Kenneth L. Dretchen 1, and Frank G. Standaert 1

1 Department of Pharmacology, Georgetown University Schools of Medicine and Dentistry, Washington, D.C. 20007

Fibers of the cat soleus muscle had a mean resting potential of 87 millivolts as measured with an intracellular microelectrode. Miniature end plate potentials had a mean amplitude of 0.95 millivolt, a mean frequency of 1.01 per second, a mean duration of 4.44 milliseconds, and a mean rate of rise of 0.99 volt per second. Two populations of response could be discerned on the basis of rate of rise. Neither agr-chloralose nor nerve section had any significant effect on the response pattern. The in vivo preparation appears to provide a superior representation of the physiology of the myoneural junction.

To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)