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Science 14 December 1973:
Vol. 182. no. 4117, pp. 1148 - 1149
DOI: 10.1126/science.182.4117.1148
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Articles

Luteinizing Hormone-Releasing Factor Potentiates Lordosis Behavior in Hypophysectomized Ovariectomized Female Rats

Donald W. Pfaff 1

1 Rockefeller University, York Avenue and 66 Street, New York 10021

Subcutaneous injection of luteinizing hormone-releasing factor (LRF) in estrogen-primed hypophysectomized, ovariectomized female rats facilitates the appearance of the lordosis response. The LRF effect on lordosis was seen 90, 180, and 360 minutes after injection. This effect could help to synchronize the female's mating behavior with the ovulatory discharge of luteinizing hormone.


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Reproductive Endocrine Disorders in Women With Partial Seizures of Temporal Lobe Origin.
A. G. Herzog, M. M. Seibel, D. L. Schomer, J. L. Vaitukaitis, and N. Geschwind (1986)
Arch Neurol 43, 341-346
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Peptides and Psychoneuroendocrinology: A Perspective.
C. B. Nemeroff and A. J. Prange Jr (1978)
Arch Gen Psychiatry 35, 999-1010
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Axonal projections of medial preoptic and anterior hypothalamic neurons.
L. Conrad and D. Pfaff (1975)
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A novel mammalian receptor for the evolutionarily conserved type II GnRH.
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