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Science 14 December 1973:
Vol. 182. no. 4117, pp. 1144 - 1146
DOI: 10.1126/science.182.4117.1144
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Articles

Alteration of Disc Formation in Photoreceptors of Rat Retina

Dennis J. Landis 1, Peter A. Dudley 1, and Robert E. Anderson 1

1 Department of Ophthalmology, Baylor College of Medicine, Houston, Texas 77025

Autoradiographic experiments demonstrate that the renewal process of the rod photoreceptors in the rat retina is altered during essential fatty acid deficiency. After the administration of tritiated amino acids, animals raised on a fat-free ration show no evidence of disc formation, while those raised on a normnal ration show disc formation and renewal. The latter process is apparently dependent upon the availability of linoleic or linolenic (or both) fatty acids.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Visual membranes: specificity of fatty acid precursors for the electrical response to illumination.
T. Wheeler, R. Benolken, and R. Anderson (1975)
Science 188, 1312-1314
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Science. ISSN 0036-8075 (print), 1095-9203 (online)