Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 9 November 1973:
Vol. 182. no. 4112, pp. 597 - 599
DOI: 10.1126/science.182.4112.597
Prev | Table of Contents | Next

Articles

Impairment of Timing Behavior after Prolonged Alcohol Consumption in Rats

Don W. Walker 1 and Gerhard Freund 2

1 Veterans Administration Hospital and Departments of Neuroscience and Psychology, University of Florida, Gainesville 32610
2 Veterans Administration Hospital and Department of Medicine, University of Florida

Prolonged alcohol consumption (5 months) concomitant with adequate nutrition was found to impair the acquisition and performance of timing behavior. Alcohol was administered in the form of a liquid diet containing 35 percent ethanol-derived calories as the only source of fluid and calories. One control group received the identical liquid diet with isocaloric substitution of sucrose for ethanol, and another control group received laboratory chow and water without restriction. Thirty days after ethanol was discontinued in the diet, the alcohol-consuming rats were severely impaired in acquisition and performance of timing behavior as compared to controls.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Neuronal loss in hippocampus induced by prolonged ethanol consumption in rats.
D. Walker, D. Barnes, S. Zornetzer, B. Hunter, and P Kubanis (1980)
Science 209, 711-713
   Abstract »    PDF »
Morphological alterations in hippocampus after long-term alcohol consumption in mice.
J. Riley and D. Walker (1978)
Science 201, 646-648
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)