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Science 2 November 1973:
Vol. 182. no. 4111, pp. 488 - 490
DOI: 10.1126/science.182.4111.488
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Articles

Hypothalamic Obesity: The Myth of the Ventromedial Nucleus

Richard M. Gold 1

1 Psychology Department, State University of New York, College at Cortlantd, Cortland 13045

Lesions restricted to the ventromedial nucleus of the hypothalamus were neither necessary nor sufficient for, and did not contribute to, the production of hypothalamic obesity. Hypothalamic lesions and knife cuts that do produce obesity damage the nearby ventral noradrenergic bundle or its terminals.


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