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Science 14 September 1973:
Vol. 181. no. 4104, pp. 1060 - 1061
DOI: 10.1126/science.181.4104.1060
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Articles

Cytomegalovirus: Conversion of Nonpermissive Cells to a Permissive State for Virus Replication

Stephen St. Jeor 1 and Fred Rapp 1

1 Department of Microbiology, College of Medicine, Pennsylvania State University, Hershey 17033

Human embryonic kidney cells are epithelioid cells which are normally nonpermissive for in vitro replication of human cytomegalovirus. These cells were converted to a permissive state for the virus by prior treatment with 5-iodo-2'-deoxyuridine. When this method was used, a nonpermissive cell was made permissive to an infecting virus.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
5-iododeoxyuridine potentiation of the replication in vitro of several unrelated RNA and DNA viruses.
J. Green and S Baron (1975)
Science 190, 1099-1101
   Abstract »    PDF »
Demonstration of the Oncogenic Potential of Herpes Simplex Viruses and Human Cytomegalovirus.
F. Rapp and J.-L. H. Li (1974)
Cold Spring Harb Symp Quant Biol 39, 747-763
   Abstract »    PDF »


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