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Science 7 September 1973:
Vol. 181. no. 4103, pp. 945 - 947
DOI: 10.1126/science.181.4103.945
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Articles

Isolation of a Neurotropic Type C Virus

J. Earle Officer 1, Nora Tecson 1, John D. Estes 2, Evelyn Fontanilla 3, Robert W. Rongey 3, and Murray B. Gardner 3

1 Department of Pathology, University of Southern California School of Medicine, Los Angeles 90033
2 Viral Carcinogenesis Branch, National Cancer Institute, Bethesda, Maryland 20014
3 Department of Pathology, University of Southern California School of Medicine

A neurogenic paralysis of the lower limb can be induced and serially transmitted in mice by a nontransforming type C virus strain that originated in an embryo of a wild mouse. The virus exerted a neurotropic effect on the anterior horn neurons.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
CSF Viral Antibodies: Evaluation in Amyotrophic Lateral Sclerosis and Late-Onset Postpoliomyelitis Progressive Muscular Atrophy.
J. E. Kurent, B. R. Brooks, D. L. Madden, J. L. Sever, and W. K. Engel (1979)
Arch Neurol 36, 269-273
   Abstract »    PDF »
A Search for Clues to the Cause of Amyotrophic Lateral Sclerosis.
R. Hanisch, R. L. Dworsky, and B. E. Henderson (1976)
Arch Neurol 33, 456-457
   Abstract »    PDF »
Mammalian Cells in Culture Frequently Release Type C Viruses.
M. M. Lieber, R. E. Benveniste, D. M. Livingston, and G. J. Todaro (1973)
Science 182, 56-59
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)