Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 17 August 1973:
Vol. 181. no. 4100, pp. 665 - 667
DOI: 10.1126/science.181.4100.665
Prev | Table of Contents | Next

Articles

Murine C-type RNA Virus from Spontaneous Neoplasms: in vitro Host Range and Oncogenic Potential

Robert L. Peters 1, Gerard J. Spahn 1, Louise S. Rabstein 1, Gary J. Kelloff 2, and Robert J. Huebner 2

1 Microbiological Associates, Inc. Walkersville, Maryland 21793
2 Viral Carcinogenesis Branch, National Cancer Institute, Bethesda, Maryland 20014

Strain BALB/c mice harbor at least two host range variants of marine leukemia virus. One variant, which is host-cell tropic, is the predominant isolate from neoplastic tissues and produced lymphoreticular neoplasms when injected into BALB/c newborn mice. A second variant, whicht is isolated throughout life, grows poorly in host embryonic cells in culture and was not associated with lymphoreticular neoplasm induction when injected into newborn BALB/c mice.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Endogenous Primate and Feline Type C Viruses.
G. J. Todaro, R. E. Benveniste, R. Callahan, M. M. Lieber, and C. J. Sherr (1974)
Cold Spring Harb Symp Quant Biol 39, 1159-1168
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)