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Science 17 August 1973:
Vol. 181. no. 4100, pp. 663 - 664
DOI: 10.1126/science.181.4100.663
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Articles

Brain Calcium: Role in Temperature Regulation

James L. Hanegan 1 and Bill A. Williams 1

1 National Aeronautics and Space Administration, Ames Research Center, Moffett Field, California 94035

Perfusion of the preoptic-anterior hypothalamus with excess calcium ion in ground squirrels produces a drop in core temperature. The magnitude of the drop is directly dependent on ambient temperature. Respiration, heart rate, and oxygen consumption are also reduced during perfusion of calcium ion. It is concluded that the depression of body temperature during calcium ion perfusion is due to generalized depression of the neurons of the preoptic-anterior hypothalamus.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)