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Science 17 August 1973:
Vol. 181. no. 4100, pp. 659 - 661
DOI: 10.1126/science.181.4100.659
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Articles

Insecticide Inhibition of 5agr-Dihydrotestosterone Binding in the Rat Ventral Prostate

Alan E. Wakeling 1 and Willard J. Visek 1

1 Department of Animal Science, Cornell University, Ithaca, New York 14850

The chlorinated hydrocarbon insecticides dieldrin and o,p'-DDT inhibit binding of 5agr-dihydrotestosterone to specific receptor proteins in rat prostate cytosol. Dieldrin is less inhibitory than o,p'-DDT.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)