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Science 3 August 1973:
Vol. 181. no. 4098, pp. 450 - 451
DOI: 10.1126/science.181.4098.450
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Articles

Esterase, Malate, and Lactate Dehydrogenases Activity in Murine Neuroblastoma

Rupi Prasad 1, Naresh Prasad 2, and Kedar N. Prasad 3

1 Department of Obstetrics and Gynecology and Department of Urology, Baylor College of Medicine, Houston, Texas 77025
2 Department of Radiology, Baylor College of Medicine, and Veterans Administration Hospital, Houston 77031
3 Department of Radiology, University of Colorado Medical Center, Denver 80220

Mouse neuroblastoma tumors have only the fifth isozyme band (A4) of lactate dehydrogenase, whereas this band is missing in the brain which contained four other bands of lactate dehydrogenase. The agr-esterase isozyme patterns of tumors, kidney, and brain are similar except that there is an additional slowest-moving form of esterase in all tumor tissues. The malate dehydrogenase pattern is not altered in any of the tissues.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)