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Science 13 July 1973:
Vol. 181. no. 4095, pp. 171 - 173
DOI: 10.1126/science.181.4095.171
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Articles

Microtubule Function in Immune and Nonimmune Lymphocyte-Mediated Cytotoxicity

Terry B. Strom 1, Marvin R. Garovoy 1, Charles B. Carpenter 1, and John P. Merrill 1

1 Department of Medicine, Peter Bent Brigham Hospital, Boston, Massachusetts 02115

Disaggregation of microtubular subunits in effector lymphocytes inhibits their ability to injure target cells. The inhibition is not reversed by denterium oxide, an agent known to stablize microtubular subunits.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)