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Science 13 July 1973:
Vol. 181. no. 4095, pp. 167 - 169
DOI: 10.1126/science.181.4095.167
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Articles

Serological Identification of an Ir-Region Product

Vecaronra Hauptfeld 1, Dagmar Klein 1, and Jan Klein 1

1 Department of Oral Biology, School of Dentistry, and Department of Human Genetics, Medical School, University of Michigan, Ann Arbor 48104

Reciprocal immunization of congenic lines differing in the middle portion of the H-2 complex leads to the production of antibodies which react with an antigen or antigens controlled by the Ir region. The antigen designated Ir-1.1 seems to be present only on a subpopulation of lymphocytes from lymph nodes and spleen. It is absent on bone marrow cells.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Polymorphic B-cell Determinants in Man.
J. J. van Rood, A. van Leeuwen, M. Jonker, A. Termijtelen, and B. A. Bradley (1977)
Cold Spring Harb Symp Quant Biol 41, 417-427
   Abstract »    PDF »
Histocompatibility-2 System of Wild Mice IV. Ia and Ir Typing of Two Wild Mouse Populations.
J. Klein, C. F. Merryman, P. H. Maurer, M. Hauptfeld, and M. B. Gardner (1977)
Cold Spring Harb Symp Quant Biol 41, 457-463
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Selective Expression of Separate I-region Loci in Functionally Different Lymphocyte Subpopulations.
D. B. Murphy, K. Okumura, L. A. Herzenberg, L. A. Herzenberg, and H. O. McDevitt (1977)
Cold Spring Harb Symp Quant Biol 41, 497-504
   Abstract »    PDF »
Inhibition of immune responses in vitro by specific antiserums to Ia antigens.
J. Frelinger, J. Niederhuber, and D. Shreffler (1975)
Science 188, 268-270
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)