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Science 6 July 1973:
Vol. 181. no. 4094, pp. 59 - 60
DOI: 10.1126/science.181.4094.59
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Articles

Crystallization of NADP-Specific Isocitrate Dehydrogenase

William F. Burke 1, James R. Swafford 1, and Henry C. Reeves 1

1 Department of Botany and Microbiology, Arizona State University, Tempe 85281

The first crystalline preparation of isocitrate dehydrogenase specific for nicotinamide adenine dinucleotide phosphate has been obtained with enzyme isolated from Escherichia coli. Scanning electron microscopy was employed to elucidate the structure of the crystals, which were found to exist as regular octahedrons ranging in size from 5 to 90 micrometers.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)