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Science 29 June 1973:
Vol. 180. no. 4093, pp. 1372 - 1374
DOI: 10.1126/science.180.4093.1372
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Articles

Alcohol-Induced Hyperlipidemia and Beta Lipoproteins

Jack H. Mendelson 1 and Nancy K. Mello 2

1 Department of Psychiatry, Harvard Medical School, Boston, Massachusetts 02118
2 Laboratory of Alcohol Research, National Institute of Alcohol Abuse and Alcoholism, Washington, D.C. 20032

Alcohol addicts with a primary type IV hyperlipoproteinemia show a striking elevation of triglycerides in the serum during long periods of alcohol consumption as compared with controls, without an accompanying significant increase in free fatty acids in the serum. These data suggest that this genetically related lipid abnormality may be a significant factor in the pathogenesis of alcohol hyperlipemia and the alcohol-induced fatty liver.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Dual Defect in Metabolism of Very-Low-Density Lipoprotein Triglycerides: Patients With Type 5 Hyperlipoproteinemia.
Y. A. Kesaniemi and S. M. Grundy (1984)
JAMA 251, 2542-2547
   Abstract »    PDF »
Significance of Alcohol-Induced Hypertriglyceridemia in Patients with Type IV Hyperlipoproteinemia.
J. H. MENDELSON and N. K. MELLO (1974)
Ann Intern Med 80, 270-271
   Abstract »    PDF »
Hyperlipemia and Alcoholic Cirrhosis.
H.T.R. (1973)
JAMA 225, 1529
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)