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Science 27 April 1973:
Vol. 180. no. 4084, pp. 410 - 413
DOI: 10.1126/science.180.4084.410
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Articles

Serotonin Producing Neuroepithelial Bodies in Rabbit Respiratory Mucosa

Joseph M. Lauweryns 1, Marnix Cokelaere 1, and Paul Theunynck 1

1 Laboratory of Histopathology, Katholieke Universiteit te Leuven, 12, Minderbroedersstraat, B-3000, Leuven, Belgium

The intrapulmonary lining epithelium of rabbits contains newly identified corpuscles composed of argyrophil, argentaffin, yellow fluorescent, ultrastructurally granulated and innervated epithelial cellular organs. These are proved, by electron microscopic cytochemistry and microspectrography, to be a source for intrapulmonary production of serotonin. Probably they are intrapulmonary neuroreceptor organs modulated by the central nervous system which exhibit local secretory activities.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)