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Science 27 April 1973:
Vol. 180. no. 4084, pp. 380 - 384
DOI: 10.1126/science.180.4084.380
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Articles

Enzyme Electrodes

David A. Gough 1 and Joseph D. Andrade 2

1 University of Utah, Salt Lake City 84112
2 The Colleges of Engineering and Pharmacy, The College of Medicine, University of Utah

From the discussion of electrodes and enzymes herein, and from the accounts of enzyme electrodes that have appeared in the literature, clinical determinations of certain metabolites and soluble enzymes by means of enzyme electrodes seem quite feasible. Such devices may be made highly specific by the use of appropriate enzymes and a high degree of accuracy can be obtained. Instantaneous and continuous determinations can be made from physiological fluids, and undesirable physiologic responses can theoretically be minimized, thus making long-term clinical monitoring a possibility. Enzyme electrodes may also have a useful lifetime and meet other practical requirements.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Membrane electrode probes for biological systems.
G. Rechnitz (1975)
Science 190, 234-238
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