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Science 30 March 1973:
Vol. 179. no. 4080, pp. 1324 - 1326
DOI: 10.1126/science.179.4080.1324
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Articles

Toxin from Fusarium moniliforme: Effects on Plants and Animals

Richard J. Cole 1, Jerry W. Kirksey 1, Horace G. Cutler 2, Ben L. Doupnik 3, and John C. Peckham 4

1 National Peanut Research Laboratory, U.S. Department of Agriculture, P.O. Box 637, Dawson, Georgia 31742
2 Georgia Coastal Plain Experiment Station, U.S. Department of Agriculture, Tifton 31794
3 College of Agriculture, South Central Station, University of Nebraska, Clay Center 68933
4 Pathology Section, Southern Research Institute, Birmingham, Alabama 35202

A mycotoxin-producing strain of Fusarium moniliforme was isolated from southern leaf blight-damaged corn seed. A water-soluble toxin, subsequently purified from the fungus, had an oral median lethal dose of 4.0 milligrams per kilogram in 1-day-old cockerels. The toxin also produced plant growth-regulating and phytotoxic effects on plant systems. Physical and chemical data presented for the toxin suggest a structurally new toxin. The trivial name "moniliformin" has been assigned to the toxin.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Individual and Combined Effects of Fumonisin B1 and Moniliformin on Clinicopathological and Cell-Mediated Immune Response in Japanese Quail.
D. Sharma, R. K. Asrani, D. R. Ledoux, N. Jindal, G. E. Rottinghaus, and V. K. Gupta (2008)
Poult. Sci. 87, 1039-1051
   Abstract »    Full Text »    PDF »
A Hemorrhagic Factor (Apicidin) Produced by Toxic Fusarium Isolates from Soybean Seeds.
J.-S. Park, K.-R. Lee, J.-C. Kim, S.-H. Lim, J.-A. Seo, and Y.-W. Lee (1999)
Appl. Envir. Microbiol. 65, 126-130
   Abstract »    Full Text »


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