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Science 16 February 1973:
Vol. 179. no. 4074, pp. 696 - 698
DOI: 10.1126/science.179.4074.696
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Articles

Quantitation of RNA Tumor Viruses and Viruslike Particles in Human Milk by Hybridization to Polyadenylic Acid Sequences

J. Schlom 1, D. Colcher 1, S. Spiegelman 1, S. Gillespie 2, and D. Gillespie 2

1 Institute of Cancer Research and Department of Human Genetics and Development, College of Physicians and Surgeons, Columbia University, New York 10032
2 Bionetics Research Laboratories, Bethesda, Maryland 20014

RNA tumor viruses and viruslike particles from human milk are quantitated by hybridization of the polyadenylic acid regions in their 60S to 70S RNA to radioactive polyribouridylic acid of known specific activity. The length of the polyadenylic acid region in the 60S to 70S RNA of the human milk particle is identical to that of the known oncogenic RNA viruses.


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