Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 26 January 1973:
Vol. 179. no. 4071, pp. 389 - 391
DOI: 10.1126/science.179.4071.389
Prev | Table of Contents | Next

Articles

Pituitary Gonadotrophs: Nuclear Concentration of Radioactivity after Injection of [3H]Testosterone

Madhabananda Sar 1 and Walter E. Stumpf 1

1 Laboratories for Reproductive Biology, Departments of Anatomy and Pharmacology, University of North Carolina, Chapel Hill 27514

Gonadotrophs and castration cells in the male rat pituitary showed nuclear concentration of radioactivity 1 hour after [1,2,6,7-3H]testosterone injection. Thyrotrophs and acidophils did not retain radioactivity; also the cells of the intermediate and posterior lobes did not accumulate radioactivity. The autoradiographic results suggest a direct and selective action of androgen on gonadotrophs, which contrasts with the action of estradiol which was shown earlier to bind not only to basophils but to acidophils and chromophobes as well.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Neurons of the Hypothalamus Concentrate [3H]Progesterone or Its Metabolites.
M. Sar and W. E. Stumpf (1973)
Science 182, 1266-1268
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)