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Science 12 January 1973:
Vol. 179. no. 4069, pp. 190 - 192
DOI: 10.1126/science.179.4069.190
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Articles

Endothelial Cell Membranes: Polarity of Particles as Seen by Freeze-Fracturing

G. P. Dempsey 1, S. Bullivant 1, and W. B. Watkins 2

1 Department of Cell Biology, University of Auckland, Auckland, New Zealand
2 Postgraduate School of Obstetrics and Gynaecology, University of Auckland

Freeze-fracturing shows particles within membranes. In plasma membranes of most cells the particles are more strongly bound to the inner half. In unfixed endothelial cells, this polarity is reversed. Glutaraldehyde fixation results in conventional polarity. The reverse polarity may be related to a mechanism for preferential fusion of pinocytotic vesicles with the plasma membrane.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Endothelial Claudin: Claudin-5/TMVCF Constitutes Tight Junction Strands in Endothelial Cells.
K. Morita, H. Sasaki, M. Furuse, and S. Tsukita (1999)
J. Cell Biol. 147, 185-194
   Abstract »    Full Text »    PDF »
Replication of Human Endothelial Cells in Culture.
L. J. Lewis, J. C. Hoak, R. D. Maca, and G. L. Fry (1973)
Science 181, 453-454
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)