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Science 22 December 1972:
Vol. 178. no. 4067, pp. 1288 - 1290
DOI: 10.1126/science.178.4067.1288

Articles

Recognition of Cancer in vivo by Nuclear Magnetic Resonance

Irwin D. Weisman 1, Lawrence H. Bennett 1, Louis R. Maxwell Sr. 2, Mark W. Woods 3, and Dean Burk 3

1 Institute for Materials Research, National Bureau of Standards, Gaithersburg, Maryland 20760
2 3506 Leland Street, Chevy Chase, Maryland 20015
3 National Cancer Institute, Bethesda, Maryland 20014

Pulsed nuclear magnetic resonance has been used to differentiate in vivo between normal mouse tail tissue and a malignant transplanted melanoma, S91, located on the tail. The tumor displayed a nuclear (proton) spin-lattice relaxation time of sim0.7 second contrasted with the simultaneously measured normal tail tissue relaxation time of sim0.3 second.


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Proton Relaxation Rates of Water in Brain and Brain Tumors.
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