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Science 1 December 1972:
Vol. 178. no. 4064, pp. 949 - 955
DOI: 10.1126/science.178.4064.949
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Articles

Chromosome Mapping in the Mouse

Fluorescence banding techniques permit assignment of most genetic linkage groups

Dorothy A. Miller 1 and Orlando J. Miller 1

1 College of Physicians and Surgeons, Columbia University, New York 10032

Chromosome banding techniques have permitted the identification of every normal chromosome in the mouse, Mus musculus, and the demonstration of strain differences. By identifying the chromosomes involved in a series of translocations, it has been possible to assign 14 of the 19 known linkage groups to 14 different chromosomes. These powerful cytological methods promise to revolutionize cytogenetic studies in higher organisms.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Genetic mapping in mammals: chromosome map of domestic cat.
S. O'Brien and W. Nash (1982)
Science 216, 257-265
   Abstract »    PDF »
Conservation of Ancient Linkage Groups in Evolution and Some Insight into the Genetic Regulatory Mechanism of X-inactivation.
S. Ohno (1974)
Cold Spring Harb Symp Quant Biol 38, 155-164
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)