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Science 1 December 1972:
Vol. 178. no. 4064, pp. 1001 - 1002
DOI: 10.1126/science.178.4064.1001
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Articles

Thymus-Dependent and Thymus-Independent Lymophocyte Separation: Relation to Exposed Sialic Acid on Cell Surface

Stig Nordling 1, Leif C. Andersson 1, and Pekka Häyry 1

1 Third Department of Pathology, University of Helsinki, SF-00290 Helsinki, Finland

On preparative cell electrophoresis mouse lymph node lymphocytes separate into fast-moving (T, thymus-dependent) and slow-moving (B, thymus-independent) fractions. After treatment with neuraminidase all lymphocytes move as one very slow fraction, indicating that the difference in the mobility of the two kinds of cells is due to differences in the density of exposed sialic acid on their surfaces.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)