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Science 20 October 1972:
Vol. 178. no. 4058, pp. 319 - 320
DOI: 10.1126/science.178.4058.319
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Articles

Adaptation of the Adrenal Medulla: Sustained Increase in Choline Acetyltransferase by Psychosocial Stimulation

Alan M. Goldberg 1 and Bruce L. Welch 2

1 Department of Environmental Medicine, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, Maryland 21205
2 Friends Medical Science Research Center, Baltimore, Maryland 21228, and Department of Psychiatry and Behavioral Science, Johns Hopkins University, Baltimore 21228

Sustained increases were produced in adrenal choline acetyltransferase of individually caged mice by placing them into groups for 10 or 15 minutes daily for 7 to 10 days. They were left undisturbed in their individual cages for the remainder of each day. As in previous experiments of similar design, adrenal catecholamines and adrenal weight were also increased, although body weight was not affected.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Catecholamine Uptake in Cerebral Cortex: Adaptive Change Induced by Fighting.
E. D. Henley, B. Moisset, and B. L. Welch (1973)
Science 180, 1050-1052
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Science. ISSN 0036-8075 (print), 1095-9203 (online)