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Science 6 October 1972:
Vol. 178. no. 4056, pp. 60 - 62
DOI: 10.1126/science.178.4056.60
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Articles

Virions from Progressive Multifocal Leukoencephalopathy: Rapid Serological Identification by Electron Microscopy

J. B. Penney Jr. 1, L. P. Weiner 1, R. M. Herndon 1, O. Narayan 1, and R. T. Johnson 1

1 Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205

Virions were extracted directly from the brain of a patient with progressive multifocal leukoencephalopathy (PML). They were treated with antiserum to SV40, with rabbit antiserum to previous PML isolates, or with serum from another patient with the same disease and observed directly by electron microscopy. This procedure could be used for the rapid identification of the antigenic nature of virions in cases of PML.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Measles virus nucleotide sequences: detection by hybridization in situ.
A. Haase, P Ventura, C. Gibbs Jr, and W. Tourtellotte (1981)
Science 212, 672-675
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Papovavirus of JC Type in Progressive Multifocal Leukoencephalopathy: Rapid Identification and Subsequent Isolation.
L. P. Weiner, O. Narayan, J. B. Penney Jr., R. M. Herndon, E. R. Feringa, W. W. Tourtellotte, and R. T. Johnson (1973)
Arch Neurol 29, 1-3
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