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Science 22 September 1972:
Vol. 177. no. 4054, pp. 1105 - 1108
DOI: 10.1126/science.177.4054.1105
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Articles

RNA Metabolism in Tracheal Epithelium: Alteration in Hamsters Deficient in Vitamin A

David G. Kaufman 1, Mary S. Baker 1, Joseph M. Smith 1, William R. Henderson 1, Curtis C. Harris 1, Michael B. Sporn 1, and Umberto Saffiotti 1

1 Lung Cancer Unit, National Cancer Institute, Bethesda, Maryland 20014

The electrophoretic pattern of RNA molecules that are synthesized in vitro in tracheal epithelium from hamsters deficient in vitamin A differs from that of RNA synthesized in normal, pair-fed control hamsters. There is less RNA of low electrophoretic mobility in the epithelial cells deficient in vitamin A. This alteration is reversed after the deficient animals have been treated with vitamin A.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Retinyl Acetate: Effect on Cellular Content of RNA in Epidermis in Cell Culture in Chemically Defined Medium.
M. B. Sporn, N. M. Dunlop, and S. H. Yuspa (1973)
Science 182, 722-723
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)