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Science 8 September 1972:
Vol. 177. no. 4052, pp. 887 - 889
DOI: 10.1126/science.177.4052.887
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Articles

Separation of Skin Reactive Intestinal Cancer Antigen from the Carcinoembryonic Antigen of Gold

Ariel C. Hollinshead 1, C. Glen McWright 1, T. Crandall Alford 1, Donald H. Glew 1, Phil Gold 2, and Ronald B. Herberman 3

1 Laboratory for Virus and Cancer Research, George Washington University Medical Center. Washington, D.C. 20037
2 Division of Clinical Immunology, McGill University Clinic, Montreal General Hospital, Montreal 109, Quebec
3 Cellular and Tumor Immunology Section, Laboratory of Cell Biology, National Cancer Institute, Bethesda, Maryland 20014

Soluble fractions of human intestinal cancer and fetal intestinal cell membranes produced delayed hypersensitivity reactions in patients with intestinal cancer. These soluble fractions and perchloric acid extracts of intestinal cancer cells were fractionated by polacrylamide-gel electrophoresis. The Gold carcinoembryonic antigen was found in a region of the gels different from that of the skin reactive antigen.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Soluble Membrane Antigens of Lip and Cervical Carcinomas: Reactivity with Antibody for Herpesvirus Nonvirion Antigens.
A. C. Hollinshead and G. Tarro (1973)
Science 179, 698-700
   Abstract »    PDF »
Carcinoembryonic Antigen Revisited.
S. C. KRAFT (1973)
Ann Intern Med 78, 147
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)