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Science 1 September 1972:
Vol. 177. no. 4051, pp. 797 - 799
DOI: 10.1126/science.177.4051.797

Articles

Mouse Leukemia: Depression of Serum Interferon Production

Jaqueline De Maeyer-Guignard 1

1 Fondation Curie-Institut du Radium (Biologie), Orsay 91, France

Production of circulating interferon is significantly impaired in AKR/J mice after development of lymphoblastic leukemia and in Balb/c mice with clinical signs of Friend erythroblastic leukemia. This alteration has been observed with three interferon inducers, each one known to elicit an interferon response in different cells.


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Science. ISSN 0036-8075 (print), 1095-9203 (online)