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Science 25 August 1972:
Vol. 177. no. 4050, pp. 720 - 722
DOI: 10.1126/science.177.4050.720
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Articles

Lysergic Acid Diethylamide and Stimulus Generalization: Rate-Dependent Effects

Linda A. Dykstra 1 and James B. Appel 1

1 Department of Psychiatry, University of Chicago, Chicago, Illinois 60637

A stimulus generalization procedure was used to investigate the effects of LSD on sensitivity to auditory stimuli in rats. The shape of the generalization gradient was changed after administration of the drug only with a dose which produced decreases in relatively high rates of responding.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)