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Science 18 August 1972: Vol. 177. no. 4049, pp. 618 - 619 DOI: 10.1126/science.177.4049.618
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Articles
Aryl Hydrocarbon (Benzopyrene) Hydroxylase Is Stimulated in Human Lymphocytes by Mitogens and Benz[a]anthracene
James P. Whitlock Jr. 1,
Herbert L. Cooper 2, and
Harry V. Gelboin 3
1 Chemistry Branch, National Cancer Institute, Bethesda, Maryland 20014
2 Cell Biology Section, Laboratory of Biochemistry, National Institute of Dental Research, Bethesda, Maryland
3 Chemistry Branch, National Cancer Institute, Bethesda, Maryland
A mixed-function oxidase that requires reduced nicotinamide adenine dinucleotide phosphate, is carbon monoxide sensitive, and is drug-metabolizing is present in human lymphocytes and is increased to different levels by treatment with phytohemagglutinin, pokeweed mitogen, and a polycyclic hydrocarbon.
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- K Robie-Suh, R Robinson, H. Gelboin, and F. Guengerich (1980)
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208, 1031-1033
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- Genetic Variation in Coumarin Hydroxylase Activity in the Mouse (Mus musculus).
- A. W. Wood and A. H. Conney (1974)
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