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Science 11 August 1972:
Vol. 177. no. 4048, pp. 524 - 525
DOI: 10.1126/science.177.4048.524
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Articles

Rapid Immunological Induction of Murine Lymphomas: Evidence for a Viral Etiology

Eugene A. Cornelius 1

1 Department of Radiology, Yale University School of Medicine, New Haven, Connecticut 06510

A graft-versus-host reaction induced in (SJL/J x C57BL/1)F1 hybrid mice by injection of SJL/J spleen cells resulted in 100 percent incidence of tumors at 40 days. Transplantation studies revealed that the tumors were antigenically C57BL/1. Since both SJL/J and C57BL/1 mice carry tumorigenic virus, the evidence suggests a viral etiology.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Malignancies After Hematopoietic Stem Cell Transplantation: Many Questions, Some Answers.
H. J. Deeg and G. Socie (1998)
Blood 91, 1833-1844
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