Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 11 August 1972:
Vol. 177. no. 4048, pp. 522 - 524
DOI: 10.1126/science.177.4048.522
Prev | Table of Contents | Next

Articles

Protein Absorption by the Intestine of the Fetal Rat in Utero

Robert Lev 1 and Donald Orlic 1

1 Departments of Pathology and Anatomy, New York Medical College, New York 10029

Horseradish peroxidase (molecular weight, about 40,000) injected into the amniotic sacs in pregnant rats has been identified ultrastructurally, 6 to 18 hours later, within the fetal intestine in the absorptive cells and the underlying vascular endothelium. This indicates that macromolecular protein within amniotic fluid swallowed by the fetus can be absorbed and transported by fetal intestine, and may indicate that physiological compounds can be transported by this enteric route to contribute to fetal development.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Insulin-Like Growth Factor II and Binding Proteins 1 and 3 from Second Trimester Human Amniotic Fluid Are Associated with Infant Birth Weight.
D. K. Tisi, X.-J. Liu, L. J. Wykes, C. D. Skinner, and K. G. Koski (2005)
J. Nutr. 135, 1667-1672
   Abstract »    Full Text »    PDF »
Total Protein Concentration in Human Amniotic Fluid Is Negatively Associated with Infant Birth Weight.
D. K. Tisi, J. J. Emard, and K. G. Koski (2004)
J. Nutr. 134, 1754-1758
   Abstract »    Full Text »
Early dietary experience influences ontogeny of intestine in response to dietary lipid changes in later life.
E. Jarocka-Cyrta, N. Perin, M. Keelan, E. Wierzbicki, T. Wierzbicki, M. T. Clandinin, and A. B. R. Thomson (1998)
Am J Physiol Gastrointest Liver Physiol 275, G250-G258
   Abstract »    Full Text »    PDF »
Review: Is Fetal Enteral Nutrition Important for Normal Gastrointestinal Growth?: A Discussion.
J. F. Trahair (1993)
JPEN J Parenter Enteral Nutr 17, 82-85
   Abstract »    PDF »
Swallowing in Fetal Sheep.
R. M. Bradley and C. M. Mistretta (1973)
Science 179, 1016-1017
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)