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Science 21 July 1972:
Vol. 177. no. 4045, pp. 281 - 282
DOI: 10.1126/science.177.4045.281
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Articles

Cytochalasin B Prevents Specific Sorting of Reaggregating Embryonic Cells

D. E. Maslow 1 and E. Mayhew 1

1 Department of Experimental Pathology, Roswell Park Memorial Institute, Bluffalo, New York 14203

The effect of cytochalasin B on specific sorting during reaggregation of embryonic chick heart and neural retina cells was studied. At a dose that did not measurably affect uptake of precursors of protein and RNA synthesis, ratios of potassium to sodium ions, and nonspecific aggregation, cytochalasin B disrupted the formation of the characteristic pattern of islands of heart cells within a retinal continuum.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)