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Science 23 June 1972:
Vol. 176. no. 4041, pp. 1340 - 1341
DOI: 10.1126/science.176.4041.1340
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Articles

Tumor Etiology and Chromosome Pattern

Felix Mitelman 1, Joachim Mark 1, Göran Levan 1, and Albert Levan 1

1 Institutes of Pathology and Genetics, University of Lund, S-221 85 Lund, Sweden

Fibrosarcomas induced in Chinese hamsters and rats by Rous sarcomla virus and 7,12-dimethylbenz(a)anthracene are associated with nonrandom chromosome variation. Although histologically indistinguishable, the tumors induced by the virus or chemical in each host species are characterized by completely different karyotypic patterns.


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