Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 9 June 1972:
Vol. 176. no. 4039, pp. 1124 - 1125
DOI: 10.1126/science.176.4039.1124
Prev | Table of Contents | Next

Articles

Feeding Produced in the Satiated Rat by Elevating the Concentration of Calcium in the Brain

R. D. Myers 1, S. A. Bender 1, M. K. Krsticacute 1, and P. D. Brophy 1

1 Laboratory of Neuropsychology, Purdue University, Lafayette, Inidiana 47907

When the concentration of calcium ions in the cerebral ventricles is elevated, a fully satiated rat eats voraciously. This feeding response is not prevented by prior intraventricular administration of alpha-or beta-adrenergic blocking agents, or other pharmacological antagonists. This supports the concept of an independent ionic mechanism, rather than a neurotransmitter one, for modulating a "set-point" for weight or hunger.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Intraventricular calcitonin inhibits gastric acid secretion.
J. Morley, A. Levine, and S. Silvis (1981)
Science 214, 671-673
   Abstract »    PDF »
Calcitonin: inhibitory effect on eating in rats.
W. Freed, M. Perlow, and R. Wyatt (1979)
Science 206, 850-852
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)