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Science 12 May 1972:
Vol. 176. no. 4035, pp. 683 - 684
DOI: 10.1126/science.176.4035.683
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Articles

Galactonic Acid in Galactosemia: Identification in the Urine

William R. Bergren 1, Won G. Ng 1, George N. Donnell 1, and Sanford P. Markey 2

1 Biochemistry and Metabolic Research Laboratories, Childrens Hospital of Los Angeles and Departments of Biochemistry and Pediatrics, School of Medicine, University of Southern California, Los Angeles 90027
2 B. F. Stolinsky Research Laboratories, John F. Kennedy Child Development Center, University of Colorado Medical Center, Denver 80220

Galactose is converted to galactonic acid in vivo in man. Galactonate was isolated from the urine of galactosemia patients who had been given galactose orally. The identity of the galactonate was established by gas-liquid chromatography and by the preparation of derivatives.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Detection of Inborn Errors of Metabolism: Galactosemia.
H. Z. Hill and T. T. Puck (1973)
Science 179, 1136-1139
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