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Science 5 May 1972:
Vol. 176. no. 4034, pp. 526 - 528
DOI: 10.1126/science.176.4034.526
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Articles

Polyadenylic Acid Sequences in the Virion RNA of Poliovirus and Eastern Equine Encephalitis Virus

John A. Armstrong 1, Mary Edmonds 2, Hiroshi Nakazato 2, Bruce A. Phillips 3, and Maurice H. Vaughan 2

1 Department of Epidemiology and Microbiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15213
2 Department of Biochemistry, Faculty of Arts and Sciences
3 Department of Microbiology, School of Medicine

Poliovirus virion RNA contains a single covalently bound sequence of polyadenylic acid which is approximately 49 nucleotides long. A single, slightly longer polyadenylic acid sequence is contained in Eastern Equine Encephalitis virus RNA. Since these viruses are otherwise dissimilar these sequences may play a common role in viral replication, possibly in translation of the viral RNA.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Molecular Typing of Enteroviruses: Current Status and Future Requirements.
P. Muir, U. Kammerer, K. Korn, M. N. Mulders, T. Poyry, B. Weissbrich, R. Kandolf, G. M. Cleator, and A. M. van Loon (1998)
Clin. Microbiol. Rev. 11, 202-227
   Abstract »    Full Text »    PDF »
Polyadenylic Acid in Visna Virus RNA.
D. Gillespie, K. Takemoto, M. Robert, and R. C. Gallo (1973)
Science 179, 1328-1330
   Abstract »    PDF »
Quantitation of RNA Tumor Viruses and Viruslike Particles in Human Milk by Hybridization to Polyadenylic Acid Sequences.
J. Schlom, D. Colcher, S. Spiegelman, S. Gillespie, and D. Gillespie (1973)
Science 179, 696-698
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)