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Science 10 March 1972:
Vol. 175. no. 4026, pp. 1117 - 1118
DOI: 10.1126/science.175.4026.1117
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Articles

Carcinoembryonic Antigen Present in Human Colonic Neoplasms Serially Propagated in Hamsters

David M. Goldenberg 1 and Hans J. Hansen 2

1 Department of Pathology, Temple University Health Sciences Center, Philadelphia, Pennsylvania 19140
2 Department of Biochemical Nutrition, Hoffmann-La Roche Inc., Nutley, New Jersey 07110

Carcinoembryonic antigen, as measured by radioimmunoassay, is present in two different human colonic tumors that have been serially transplanted and maintained in the cheek pouches of unconditioned, adult golden hamsters. This finding shows that a human tumor-associated antigen can be produced in an animal host.


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