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Science 14 January 1972:
Vol. 175. no. 4018, pp. 204 - 205
DOI: 10.1126/science.175.4018.204

Articles

Cell-Mediated Tumor Allograft Immunity: In vitro Transfer with RNA

Vinay Likhite 1 and Alec Sehon 1

1 Laboratory for Biophysical and Immunochemistry, Department of Chemistry, McGill University, Montreal 110, Quebec, Canada

Specific inhibition of migration of spleen cells from C57B1/6J mice, which had rejected A/J sarcoma-1 tumors, occurred in the presence of A/J lymph mode antigens. The migration inhibitory effect was transferable to normal C57B1/6J spleen cells by RNA extracted from lymph nodes and spleens of immunized animals.





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Science. ISSN 0036-8075 (print), 1095-9203 (online)