Cell-Mediated Tumor Allograft Immunity: In vitro Transfer with RNA
Vinay Likhite 1 and
Alec Sehon 1
1 Laboratory for Biophysical and Immunochemistry, Department of Chemistry, McGill University, Montreal 110, Quebec, Canada
Specific inhibition of migration of spleen cells from C57B1/6J mice, which had rejected A/J sarcoma-1 tumors, occurred in the presence of A/J lymph mode antigens. The migration inhibitory effect was transferable to normal C57B1/6J spleen cells by RNA extracted from lymph nodes and spleens of immunized animals.