Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Site Tools

  • AAAS
  • Subscribe
  • Feedback

Site Search

Search Advanced

Science 14 January 1972:
Vol. 175. no. 4018, pp. 198 - 199
DOI: 10.1126/science.175.4018.198
Prev | Table of Contents | Next

Articles

Activation of Viruses in Human Tumors by 5-Iododeoxyuridine and Dimethyl Sulfoxide

Sarah E. Stewart 1, George Kasnic Jr. 1, Catherine Draycott 1, and Theresa Ben 2

1 School of Medicine, Georgetown University, Washington, D.C. 20007
2 National Cancer Institute, Bethesda, Maryland 20014

Dimethyl sulfoxide added to cultures first treated with 5-iododeoxyuridine increased C-type virus production approximately tenfold in a human rhabdomyosarcoma cell line. 5-Iododeoxyuridine followed by dimethyl sulfoxide also activated a similar C-type virus in a metastatic tumor from a bronchial node taken from a 52-year-old male.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Cultures of Tissues From Patients With Amyotrophic Lateral Sclerosis.
N. E. Cremer, L. S. Oshiro, F. H. Norris Jr., and E. H. Lennette (1973)
Arch Neurol 29, 331-333
   Abstract »    PDF »
Observations of Apparent C-Type Particles in Baboon (Papio cynocephalus) Placentas.
S. S. Kalter, R. J. Helmke, M. Panigel, R. L. Heberling, P. J. Felsburg, and L. R. Axelrod (1973)
Science 179, 1332-1333
   Abstract »    PDF »
Isolation of RNA Virus from Papillary Tumors of the Human Renal Pelvis.
A. Y. Elliott, E. E. Fraley, P. Cleveland, A. E. Castro, and N. Stein (1973)
Science 179, 393-395
   Abstract »    PDF »
Type C Virus from Cell Cultures of Chemically Induced Rat Hepatomas.
I. B. Weinstein, R. Gebert, U. C. Stadler, J. M. Orenstein, and R. Axel (1972)
Science 178, 1098-1100
   Abstract »    PDF »
Hybridization of Burkitt Lymphoblastoid Cells.
R. Glaser and F. J. O'Neill (1972)
Science 176, 1245-1246
   Abstract »    PDF »
Intracisternal A Particles and C Particles.
A. J. Dalton and S. E. Stewart (1972)
Science 176, 319
   PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)