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Science 3 December 1971:
Vol. 174. no. 4013, pp. 1020 - 1022
DOI: 10.1126/science.174.4013.1020
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Articles

Crystal Structure of a Naturally Occurring Dinucleoside Monophosphate: Uridylyl (3',5') Adenosine Hemihydrate

J. Rubin 1, T. Brennan 1, and M. Sundaralingam 1

1 Department of Biochemistry and Laboratory of Molecular Biology, College of Agricultural and Life Sciences, University of Wisconsin, Madison 53706

The crystal structure of uridylyl (3',5') adenosine hemihydrate has been analyzed by x-ray diffraction. The two independent molecules found in the asymmetric unit exhibit conformations that differ significantly from those found in double-helical RNA. The conformational information obtained from this analysis provides considerable insight into the possible conformations of nonhelical "loop" regions of transfer RNA, as well as single-stranded regions of nucleic acids in general.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Structure of a Dinucleotide: Thymidylyl-(5'rarr3')-Thymidylate-5' (pTpT).
N. Camerman, J. K. Fawcett, and A. Camerman (1973)
Science 182, 1142-1143
   Abstract »    PDF »
Nucleotide Conformafions.
S. Arnott, D. W. L. Hukins, J. Rubin, T. Brennan, and M. Sundaralingam (1972)
Science 177, 451-452
   PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)