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Science 26 November 1971:
Vol. 174. no. 4012, pp. 951 - 952
DOI: 10.1126/science.174.4012.951
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Articles

6beta-Hydroxy-dgr1-Tetrahydrocannabinol Synthesis and Biological Activity

Zvi Ben-Zvi 1, Raphael Mechoulam 1, Habib Edery 2, and Gila Porath 2

1 Laboratory of Natural Products, Hebrew University Pharmacy School, Jerusalem, Israel
2 Israel Institute for Biological Research, Ness Ziona, and Tel-Aviv University Medical School, Tel-Aviv, Israel

6beta-Hydroxy-dgr1-tetrahydrocannabinol, a metabolite of dgr1-tetrahydrocannabinol has been synthesized from dgr6-tetrahydrocannabinol. It shows high tetrahydrocannabinol-type activity in rhesus monkeys. The implications of this funding are discussed.

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Science. ISSN 0036-8075 (print), 1095-9203 (online)