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Science 12 November 1971:
Vol. 174. no. 4010, pp. 707 - 709
DOI: 10.1126/science.174.4010.707
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Articles

Mendelian and Uniparental Alterations in Erythromycin Binding by Plastid Ribosomes

Laurens J. Mets 1 and Lawrence Bogorad 1

1 Harvard University, Biological Laboratories, Cambridge, Massachusetts 02138

Erythromycin binds specifically to the 52S subunit of the chloroplast ribosome of Chlamydomonas reinhardi. A number of erythromycin-resistant mutants whose ribosomes have lost their affinity for the antibiotic have been isolated, but the sedimentation properties of their ribosomes are indistinguishable from those of the wild-type strain. These mutants represent at least three genetic loci. Two of them show Mendelian inheritance, and one of them is inherited in a uniparental manner.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Molecular Markers for Rapidly Identifying Candidate Genes in Chlamydomonas reinhardtii: ERY1 and ERY2 Encode Chloroplast Ribosomal Proteins.
A. K. Bowers, J. A. Keller, and S. K. Dutcher (2003)
Genetics 164, 1345-1353
   Abstract »    Full Text »    PDF »
Constitutive and conditional suppression of exogenous and endogenous genes by anti-sense RNA.
J. Izant and H Weintraub (1985)
Science 229, 345-352
   Abstract »    PDF »
Evolution of organelles and eukaryotic genomes.
L Bogorad (1975)
Science 188, 891-898
   PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)