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Science 12 November 1971:
Vol. 174. no. 4010, pp. 694 - 696
DOI: 10.1126/science.174.4010.694
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Articles

Viral RNA Polymerases: Electron Microscopy of Reovirus Reaction Cores

S. Gillies 1, S. Bullivant 1, and A. R. Bellamy 1

1 Department of Cell Biology, University of Auckland, Auckland, New Zealand

The Kleinschmidt technique has been used to observe reovirus cores that have synthesized messenger RNA. Some individual viral cores probably synthesize all ten messenger RNA molecules in vitro. Each messenger RNA molecule appears to be attached to a different site on the core surface, implying that there are probably a number of different enzymic sites in each core.


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