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Science 3 September 1971:
Vol. 173. no. 4000, pp. 921 - 923
DOI: 10.1126/science.173.4000.921

Articles

Homograft Rejection Delayed by Treatment of Donor Tissue in vitro with Antilymphocyte Serum

Ronald M. Burde 1, Stephen R. Waltman 1, and Juan H. Berrios 1

1 Department of Ophthalmology, Washington University School of Medicine, St. Louis, Missouri 63110

Treatment of rabbit corneal tissue in vitro with pooled rabbit serum delays the onset of corneal homograft rejection in the host. Addition of antilymphocyte serum results in a further significant delay in the onlset of rejection. The mechanisms by which such treatment of donor tissues may modify the antigenic content of the material are discussed.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Immunologic Modification: A Basic Survival Mechanism.
B. B. Jacobs and D. E. Uphoff (1974)
Science 185, 582-587
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Science. ISSN 0036-8075 (print), 1095-9203 (online)