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Science 27 August 1971:
Vol. 173. no. 3999, pp. 845 - 847
DOI: 10.1126/science.173.3999.845
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Articles

Serum Parathyroid Hormone in X-Linked Hypophosphatemia

Claude Arnaud 1, Francis Glorieux 2, and Charles Scriver 2

1 Department of Endocrine Research, Mayo Clinic, Rochester, Minnesota 55901
2 Debelle Laboratory for Biochemical Genetics, McGill University-Montreal Children's Hospital Research Institute, Montreal 108, Quebec

Serum immunoreactive parathyroid hormone(IPTH) is normal in patients with X-linked hypophosphatemic rickets who are not treated with phosphate salts. Phosphate raises IPTH in these patients. Endogenous IPTH does not influence the existing defect in tubular reabsorption of phosphate in male patients.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Parathyroidectomy for Tertiary Hyperparathyroidism Associated With X-linked Dominant Hypophosphatemic Rickets.
R. M. Savio, J. E. Gosnell, S. Posen, T. S. Reeve, and L. W. Delbridge (2004)
Arch Surg 139, 218-222
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Four cases of acquired hypophosphataemic ('oncogenic') osteomalacia. Problems of diagnosis, treatment and long-term management.
G. P. R. Clunie, P. E. Fox, and T. C. B. Stamp (2000)
Rheumatology 39, 1415-1421
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Positional cloning of the PEX gene: new insights into the pathophysiology of X-linked hypophosphatemic rickets.
M. J. Econs and F. Francis (1997)
Am J Physiol Renal Physiol 273, F489-F498
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Supranormal 25-Hydroxyvitamin D and Subnormal 1,25-Dihydroxyvitamin D: Their Role in X-linked Hypophosphatemic Rickets.
R. W. Chesney, R. B. Mazess, P. Rose, A. J. Hamstra, and H. F. DeLuca (1980)
Arch Pediatr Adolesc Med 134, 140-143
   Abstract »    PDF »
Familial Hypophosphatemic Rickets: A Delineation of Its Subdivisions and Pathogenesis.
J. Walton (1976)
Clinical Pediatrics 15, 1007-1012
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Vitamin D-Resistant Rickets and Parathyroid Adenomas: Renal Transport of Phosphate.
Y. B. Talwalkar, J. E. Musgrave, N. R. M. Buist, R. A. Campbell, and J. R. Campbell (1974)
Arch Pediatr Adolesc Med 128, 704-708
   Abstract »    PDF »
Renal Transplantation in Hypophosphatemia With Vitamin D-Resistant Rickets.
J. M. Morgan, W. L. Hawley, A. I. Chenoweth, W. J. Retan, and A. G. Diethelm (1974)
Arch Intern Med 134, 549-552
   Abstract »    PDF »
Excretion of Phosphate and Calcium: Physiology of Their Renal Handling and Relation to Clinical Medicine.
S. G. Massry, R. M. Friedler, and J. W. Coburn (1973)
Arch Intern Med 131, 828-859
   Abstract »    PDF »
Familial Hypophosphatemic Rickets: Defective Transport of Inorganic Phosphate by Intestinal Mucosa.
E. M. Short, H. J. Binder, and L. E. Rosenberg (1973)
Science 179, 700-702
   Abstract »    PDF »
Loss of a Parathyroid Hormone-Sensitive Component of Phosphate Transport in X-Linked Hypophosphatemia.
F. Glorieux and C. R. Scriver (1972)
Science 175, 997-1000
   Abstract »    PDF »


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Science. ISSN 0036-8075 (print), 1095-9203 (online)